The UltraClean™ Microbial RNA Isolation Kit is designed to isolate high-quality RNA from microorganisms. A variety of microorganisms including bacterial spores and fungal types have been tested with this kit.

Microbial cells are added to a bead beating tube containing beads, bead solution and lysis solution. The cells are lysed by mechanical action on a vortex. The lysate is centrifuged through a spin filter. RNA is bound to the spin filter due to the high salt nature of the binding buffer. The filter is washed and the RNA is recovered in certified RNase-free elution buffer.