1) Performing new animal tests to determine unknown LD50 values in the course of the GOTS assessment

procedure for inputs (refer to Section 2.3.3) is prohibited. Instead, alternative methods (e.g. Acute Toxicity Estimates (ATE); conclusions on analogy from similar products; validated structure-activity relationships; calculation from available data of substances contained; expert judgment; in vitro tests) shall be

used to determine unknown values.

GOTS 投入物評(píng)估程序（參照第 2.3.3 節(jié)）禁止用新的動(dòng)物試驗(yàn)未知的 LD50 值。未知值應(yīng)采用其它替代

方法[如：急毒性估計(jì)值（ATE）、類似產(chǎn)品的類推結(jié)論、已驗(yàn)證的構(gòu)效關(guān)系、根據(jù)所含物質(zhì)現(xiàn)有數(shù)據(jù)進(jìn)行

計(jì)算、專家評(píng)定、體外試驗(yàn)]來判定。

2) Substances and preparations, such as alkalis and acids that fail to meet this requirement because of

their pH value only, are exempt from this requirement.

僅由于酸堿值導(dǎo)致的不符合此要求的物質(zhì)和配制品（諸如：酸和堿）則除外。

3) Performing new fish and daphnia tests to determine unknown LC50 / EC50 values in the course of the

GOTS assessment procedure for inputs is prohibited. Instead, alternative methods such as Acute Toxicity Estimates (ATE); validated structure-activity relationships; conclusion on analogy from similar products;

calculation from available data of substances contained; fish egg test (embryo toxicity test (FET)); in vitro

test; IC50 algae; OECD 201 [72hr] shall be used to determine unknown values.

可接受的測(cè)試方法 [測(cè)試時(shí)間]：GOTS 投入物評(píng)估程序禁止采用新的魚類和溞試驗(yàn)未知的 LC50/ EC50

值。未知的 LC50/ EC50 值應(yīng)采用 OECD 203 [96 小時(shí)]和 OECD 202EC50 溞[48 小時(shí)] 之外的其它方法

{如：急毒性估計(jì)值（ATE）、已驗(yàn)證的構(gòu)效關(guān)系、類似產(chǎn)品的類推結(jié)論、根據(jù)所含物質(zhì)現(xiàn)有數(shù)據(jù)進(jìn)行計(jì)

算、魚卵實(shí)驗(yàn)[胚胎毒性試驗(yàn)（FET）]、體外試驗(yàn)}來判定；IC50 藻, OECD 201 [72 小時(shí)]

4) Accepted test methods: OECD 301A, OECD 301E, ISO 7827, OECD 302A, ISO 9887, OECD 302B, ISO

9888 or OECD 303A; alternatively, to meet the 70% level a preparation tested with one of the methods

OECD 303A or ISO 11733 a percentage degradation of at least 80% shall be shown - or if tested with

one of the methods OECD 301B, ISO 9439, OECD 301C, OECD 302C, OECD 301D, ISO 10707, OECD

301F, ISO 9408, ISO 10708 or ISO 14593, a percentage degradation of at least 60% shall be shown. To

meet the 95% level, if tested with any of the mentioned methods, a percentage degradation of 95% shall

be shown. Testing duration with each method is 28 days.

可接受的測(cè)試方法：OECD 301 A、OECD 301 E、ISO 7827、OECD 302 A、ISO 9887、OECD 302

B、ISO 9888 或 OECD 303 A；對(duì)于需達(dá)到 70%生物降解率的配制品，還可采用 OECD 303A 或 ISO

11733 方法來測(cè)試，但降解性測(cè)試結(jié)果應(yīng)顯示至少達(dá)到 80%，或者采用 OECD 301 B、ISO 9439、

OECD 301 C、OECD 302 C、OECD 301D、ISO 10707、OECD 301 F、ISO 9408、ISO 10708 或 ISO14593 方法測(cè)試，但測(cè)試結(jié)果應(yīng)顯示至少達(dá)到 60%。對(duì)于需達(dá)到 95%生物降解率的配制品，不論采用上

述哪種測(cè)試方法，其測(cè)試結(jié)果應(yīng)顯示達(dá)到 95%。各測(cè)試方法的測(cè)試時(shí)間都為 28 天。